107.00 Hematological Disorders
Sickle cell disease. Refers to a chronic hemolytic anemia associated with sickle cell hemoglobin, either homozygous
or in combination with thalassemia or with another abnormal hemoglobin (such as C or F).
Appropriate hematologic evidence for sickle cell disease, such as hemoglobin electrophoresis must be included.
Vaso-occlusive, hemolytic, or aplastic episodes should be documented by description of severity, frequency, and duration.
Disability due to sickle cell disease may be solely the result of a severe, persistent
anemia or may be due to the combination of chronic progressive or episodic manifestations in the presence of a less severe
Major visceral episodes causing disability include meningitis, osteomyelitis,
pulmonary infections or infarctions, cerebrovascular accidents, congestive heart failure, genito-urinary involvement, etc.
B. Coagulation defects. Chronic inherited coagulation disorders must be documented
by appropriate laboratory evidence such as abnormal thromboplastin generation, coagulation time, or factor assay.
107.01 Category of Impairments, Hematological Disorders
107.03 Hemolytic Anemia (due to any cause). Manifested by persistence of hematocrit of 26 percent or less despite
prescribed therapy, and reticulocyte count of 4 percent or greater.
107.05 Sickle cell disease. With:
A. Recent, recurrent severe vaso-occlusive
crises (musculoskeletal, vertebral, abdominal); or
B. A major visceral complication
in the 12 months prior to application; or
C. A hyperhemolytic or aplastic crisis
within 12 months prior to application; or
D. Chronic, severe anemia with persistence
of hermatocrit of 26 percent or less; or
E. Congestive heart failure, cerebrovascular
damage, or emotional disorder as described under the criteria in 104.02, 111.00ff, or 112.00ff.
107.06 Chronic idiopathic thrombocytopenic purpura of childhood. With purpura and thrombocytopenia
of 40,000 platelets/cu.mm. or less despite prescribed therapy or recurrent upon withdrawal of treatment.
107.08 Inherited coagulation disorder. With:
A. Repeated spontaneous
or inappropriate bleeding; or
B. Hemarthrosis with joint deformity.